Effect of Panax notoginseng saponins on anti-platelet aggregation
10.3760/cma.j.issn.1673-4203.2009.01.015
- VernacularTitle:三七皂甙抗血小板聚集作用的临床观察
- Author:
Jianyu ZHANG
;
Lan PENG
;
Dinghua LIU
- Publication Type:Journal Article
- Keywords:
panax notoginseng saponins;
aspirin;
platelet aggregation
- From:
International Journal of Surgery
2009;36(1):38-40
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of Panax notoginseng saponins and aspirin on platelet aggregation and analyzed resistance probability.Methods One hundred and twenty patients with cerebral infarction were di-vided randomly into Panax notoginseng saponins group and the aspirin group (each group 30 cases),respectively treated with adenosine diphosphatc (ADP),arachidonic acid (AA) to induced and detect the largest platelet aggre-gation (MAR).All patients received platelet aggregation test in hospital on the first and 14th day.Results In Pa-nax notoginseng saponins group and the aspirin group platelet aggregation induced by gents in the same role did not show statistical significance.There were resistances,semi-resistance phenomenon.Conclusions Panax notogin-seng saponins on platelet aggregation and the impact of aspirin was not significant; it may be used as anti-platelet aggregation drug,but there is also the resistance phenomenon.By combining Panax notoginseng saponins other an-ti-platelet drug anti-platelet aggregation of the long-term clinical.It might solve the resistance problem through large-scale clinical trials.
