Primary cutaneous lymphomas:a clinicopathologicul study
10.3760/cma.j.issn.1673-422X.2009.01.024
- VernacularTitle:原发性皮肤淋巴瘤的临床病理学观察
- Author:
Wenting HUANG
;
Xiaoli FENG
;
Yuntian SUN
;
Jianming YING
;
Hongtu ZHANG
;
Susheng SHI
;
Xiuyun LIU
- Publication Type:Journal Article
- Keywords:
Lymphoma;
Skin neoplasms;
Immunohistochemistry
- From:
Journal of International Oncology
2009;36(1):76-80
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical, histopathological and immunohistochemistric features of different types of primary cutaneous lymphomas.Methods 17 cases of primary cutaneous lymphomas were ret-rospectively reviewed.All cases were classified according to the WHO-EORTC(World Health Organization-Eu-ropean Organization for Research and Treatment of Cancer) classification system combined with morphology and immunobistochemistry.The clinicopathological features of each type were observed and summarized.Results Among the 17 cases, male were 10, female were 7.The average age was 51 years old (from 16 to 78).All pa-tients visited the doctor for skin diseases 14 cases were T-cell lymphoma including 5 cases of primary cutaneous anaplastic large cell lymphuma, 2 cases of mycosis fungoides, 4 cases of subcutaneous panniculitis-like T-cell lymphoma, and 3 cases of primary cutaneous peripheral T- cell lymphomas (including 1 primary cutaneous ag-gressive epidermotropic CD8+ cytotoxic T-cell lymphoma).3 cases were B-cell lymphoma including 2 diffuse large B-cell lymphoma, leg-type and 1 primary cutaneous follicle center lymphoma.Conclusion The clinical behaviors and pathological characteristics of primary cutaneous lymphomas were complicated and variant.Nei-ther of them could be neglected in the diagnosis.