Association of serum matrix metalloproteinase-9 levels and C-reactive protein with peripheral vascular disease of lower limbs in type 2 diabetes mellitus
10.3760/cma.j.issn.1000-6699.2009.01.021
- VernacularTitle:2型糖尿病患者血清MMP-9、CRP与下肢血管病变的关系
- Author:
Qingying TAN
;
Hong LI
;
Jing WANG
;
Jun CHENG
- Publication Type:Journal Article
- Keywords:
Matrix metalloproteinase-9;
C-reactive protein;
Diabetes mellitus,type 2;
Angiopathy
- From:
Chinese Journal of Endocrinology and Metabolism
2009;25(1):68-69
- CountryChina
- Language:Chinese
-
Abstract:
Serum matrix metalloproteinase-9 (MMP-9), hypersensitive C-reactive protein (hsCRP) and other clinical parameters were measured in patients with types 2 diabetes mellitu (with or without angiopathy of lower limbs). The serum levels of MMP-9 and hsCRP were higher in type 2 diabetic patients and those with angiopathy by Doppler ultrasonography than those in normal controls. The change of serum MMP-9 was positively correlated with the level of hsCRP. The extent of angiopathy was correlated positively with both hsCRP and MMP-9.
