The treatment of postoperative local recurrence of periampullary carcinoma

VernacularTitle:壶腹周围癌术后局部复发的治疗
Author: Lun FEI ; Jianying LOU ; Hanting LIN ; Dan WU
Publication Type:Journal Article
Keywords: Ampulla of Vater; Neoplasm recurrence,local; Catheter ablation; Ultrasonic therapy
From: Chinese Journal of General Surgery 2009;24(1):20-22
CountryChina
Language:Chinese
Abstract: Objective To evaluate the treatment modalities for local recurrent periampullary carcinoma. Methods From January 1997 to May 2007, 23 patients with local recurrent periampullary carcinoma underwent different therapy. The recurrent tumor was resected through laparotomy in 3 cases and the unresectable tumors were treated with radiofrequency ablation(RFA) in 5 patients. In 10 patients and 5 patients respectively high intensity focused ultrasound ( HIFU ) and regional chemotherapy ( RC ) were performed. Results The resection rate for local recurrent periampullary carcinoma was 13% in this group, 2 patients have survived for 10 months and 13 months respectively after reoperation while one patient achieved tumor-free survival for six months so far. The symptoms were alleviated to some extent in 20 patients treated with RFA, HIFU or RC. Conclusions Resection of local recurrent periampullary carcinoma may benefit a longer survival time, and the improvement of the quality of life. RFA, HIFU and RC are the alternative modalities for patients with unresectable tumors.