A new experimental carotid siphon aneurysm model in canine based on the MR angiography and rapid prototyping technology
10.3760/cma.j.issn.1005-1201.2009.01.020
- VernacularTitle:基于MR血管成像数据和快速原型技术建立类似于人颈内动脉虹吸段动脉瘤的犬模型
- Author:
Jian XIE
;
Minghua LI
;
Huaqiao TAN
;
Yueqi ZHU
;
Chunhua FAN
;
Dingjun HU
;
Ruihua QIAO
- Publication Type:Journal Article
- Keywords:
Magnetic resonance angiography;
Carotid artery,internal;
Intracranial aneurysm
- From:
Chinese Journal of Radiology
2009;43(1):78-81
- CountryChina
- Language:Chinese
-
Abstract:
Objective The aim of the experiment is to make an intracranial aneurysm model in canine.Methods A digital tube was made based on raw magnetic resonance images of the human intracraaial carotid artery.Then 6 tubes were made in the 3 D rapid prototyping machine and coated with silicone.Finally we isolated the common carotid arteries of 6 canines and made them go through the tubes and anastomosed them end-to-side to get the aneurysm model.Six stents were implanted after one week.Results Six aneurysm models were successfully made in canines.The parent artery had similar geometrv of the human carotid siphon.All the aneurysms and parent arteries were patent in one week's follow-up.One canine died of excessive anesthesia after stentingr Two vaseular models kept patent in one month without stenosis.The other 3 had some stenosis on the bends of the vessel.Conclusions The aneurysm model in tIle experiment has high flexibility and reliability.The model provides an effective tool for research and testing neurovascular devices.It's also a useful device to train the neuroradiologists and interventional physicians.
