The research of the correlation of the changes of routine coagulation index and D-dimmer with postpartum hemorrhage
10.3760/cma.j.issn.1008-6706.2009.01.015
- VernacularTitle:常规凝血指标及D-二聚体与产后出血的关系研究
- Author:
Huaiyu LI
- Publication Type:Journal Article
- Keywords:
Parturition;
Postpartum hemorrhage;
D dimmer
- From:
Chinese Journal of Primary Medicine and Pharmacy
2009;16(1):30-31
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the correlation of the changes of routine coagulation index and D-dimmer(D-D) with postpartum hemorrhage. Methods 37 patients with postpartum hemorrhage were divided into 2 groups ac-cording to the quantity of bleeding(group 1,27 patients, postpartum hemorrhage 500 ～ 800ml; group 2,10 patients, postpartum hemorrhage more than g00ml) and 30 patients with normal deliveries as control. Routine congulation in-dex, activated partial thromboplastin time(APIT) ,prothrombin time(PT) ,thrombin time(13") ,fibrinogen(Fg) and D-D were detected during the end of delivery and 48 hours after delivery. Results Compare with control group at the end of the delivery in group 1 ,the D-D was remarkably increased (P<0.05) ,but there was no significant difference of the routine coagulation index compared with control group (P > 0.05), in group 2, the D-D, PT, APTT were in-creased, whereas the Fg was decreased (P < 0.05). 48 hours after delivery, compared with control group,the D-D was significantly higher(P < 0.05), whereas the routine coagulation index had no significant difference (P > 0.05). The lowering of D-D, increase of Fg were higher in group 2 than those in group 1 (P < 0.05). Conclusion It has impor-tant clinical significance to timely monitor routine coagulation index and D-D at the end of delivery and after delivery for understanding the coagulation function of parturient and preventing disseminated intravascular coagulation.
