Comparative study of clinical and pathological features of atypical lupus nephritis
10.3760/cma.j.issn.1008-6706.2009.01.039
- VernacularTitle:非典型狼疮肾炎的临床和病理分析
- Author:
Zhiqing HUANG
;
Dong LIANG
;
Yongzhi XU
;
Pingping HUANG
- Publication Type:Journal Article
- Keywords:
Lupus erythematosus;
Systemic;
Lupus nephritis;
Pathology
- From:
Chinese Journal of Primary Medicine and Pharmacy
2009;16(1):73-74
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical value of renal biopsy in the diagnosis of atypical lupus nephri-tis(LN). Methods The clinical and renal pathological data of 28 cases with atypical LN were analyzed retrospective-ly. Results All 28 patients could not fulfill the ACR diagnostic criterion,misdiagnosed as primary nephritic syndrome 21 eases,chronic glomerulone-phritis syndrome 4 cases ,asymptomatic hematuria 2 cases and asymptomatic proteinuria 2 cases,all renal biopsy showed changes consistent to lupus nephritis,pathological types:3 cases were class Ⅱ,4 cases were class Ⅲ,21 cases were class Ⅳ ,7 cases were class Ⅴ,2 cases was class Ⅳ+ Ⅴlupus nephritis,the clinical manifestations of nephritic syndrome were mostly pathological type Ⅳ and Ⅴ, the chronic glomerulonephritis syndrome showed diversification of pathological type, asymptomatic hematuria and/or proteinuria were mostly pathological type Ⅱ and Ⅲ. Conclusion clinical manifestations of atypical LN is no specific and easy to be misdiagnosed. Renal bi-opsy has great value in the diagnosis of atypical LN.