Evaluation of postoperative short·-term survival rate after liver transplantation for benign end-stage hepatopathy by model for end-stage liver disease score and serum sodium concentration and ascites condition
10.3760/cma.j.issn.1673-9752.2009.01.014
- VernacularTitle:终末期肝病模型评分和血清钠浓度及腹水情况评估良性终末期肝病肝移植的预后
- Author:
Zhishi CAI
;
Yi JIANG
;
Lizhi Lü
;
Xiaojin ZHANG
;
Qiucheng CAI
- Publication Type:Journal Article
- Keywords:
Liver transplantation;
Prognosis;
Serum sodium concentration;
Ascites;
Model for end-stage liver disease score
- From:
Chinese Journal of Digestive Surgery
2009;8(1):36-38
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficiency of model for end-stage liver disease(MELD)score,serum sodium concentration and aseites condition in the evaluation of short-term survival rate of patients with benign end-stage hepatopathy after liver transplantation.Methods The clinical data of 98 patients with benign end-stage hepatopathy who had undergone liver transplantation in Fuzhou General Hospital from January 1999 to February 2007 were retrospectively analyzed.The relationship between serum sodium concentration.ascites condition and the prognosis of patients with the same MELD score was analyzed.Kaplan-Meier survival curve was drawn.The 1-year survival rate of the patients was analyzed by chi-square test.The mortality of patients with the same MELD score at the end of the third month after operation was analyzed by Fisher's exact test.Results MELD score of aIJ patients was 15-25 or>25.The postoperatire 3-month mortality rates of patients with serum sodium concentration≥130 mmol/L were 5%and 15%.which were significantly lower than 33%and 55%of those with serum sodium concentration<1 30 mmol/L.The difference upon 1-year survival rates between them had statistical significance(x2:12.88,P<0.05).The postoperative 3-month mortality rates of patients without ascites were 5%and 8%.which were lower than 35%and 57%of those with aseites.and the difference upon 1-year survival rates between them had statistical significance(X2=15.26.P<0.05).Conclusions It is more accurate to evaluate the short-term survival rate after liver transplantation for benign end-stage hepatopathy by combining the MELD score with serum sodium concentration and ascites condition.