Comparision the effectiveness of CV8 with artesunate plus primaquine combination for on patients with uncomplicated P. falciparum malaria at Binh Thuan and Khanh Hoa, Viet Nam
- Author:
Nguyen Van Tien
- Publication Type:Journal Article
- Keywords:
malaria
- MeSH:
Malaria, Primaquine, Malaria, Falciparum
- From:Journal of Medical Research
2005;37(4):25-28
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
224 patients with uncomplicated P. falciparum malaria were randomly devided into two groups receiving CV8 treatment (123 patients) and artesunate+primaquine (As+Pri) (101 patients). Results: The lately recurrence rate of CV8 treatment was 3.3% and of As+Pri was 17.8%, the difference had statistic significance (p<0.05). Mean time for fever clearance of CV8 was 22.5 hours, was the same as AS+Pri (21.8 hours). The inhibitory gametocidel effect on CV8 on P.falciparum has been seen and it help elimination of dissermination. The side effects such as nausea (13.8%), vomitting (4.9%) in CV8 treated groups were the same in AS+Pri groups. These effects were often self-limited. There were no hemoglobinuria case.
