A Case of Polyarteritis Nodosa Manifesting as a Neuropathy Following Influenza Infection.
10.4078/jrd.2012.19.3.163
- Author:
Dong Hwa LEE
1
;
Jung Ho HAN
;
Mi Kyoung KIM
;
Ok Jun LEE
;
Kwi Young KANG
Author Information
1. Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, Korea. kykang@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Polyarteritis nodosa;
Influenza infection;
Neuropathy
- MeSH:
Aged;
Arteries;
Biopsy;
Cyclophosphamide;
Female;
Fever;
Foot;
Hand;
Humans;
Hyperesthesia;
Influenza, Human;
Ischemia;
Korea;
Lower Extremity;
Mononeuropathies;
Organic Chemicals;
Polyarteritis Nodosa;
Polyneuropathies;
Recurrence;
Skin;
Sural Nerve;
Vasculitis
- From:Journal of Rheumatic Diseases
2012;19(3):163-167
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Polyarteritis nodosa (PAN) is a necrotizing vasculitis of the medium-sized arteries. The symptoms and signs of PAN include purpuric skin lesions, mononeuritis multiplex, symptoms of mesenteric ischemia, and renal involvement. We report the first case of PAN manifesting as a neuropathy after influenza infection in Korea. A 68-year-old woman had fever, myalgia, hyperesthesia of both hand and foot, and lower extremity weakness. EMG findings showed severe sensorimotor polyneuropathy, such as multiple mononeuritis. A sural nerve biopsy showed vasculitis and Influenza A (H1N1) were positive. Our patient was treated by glucocorticoid and oral cyclophosphamide, thereafter, symptoms and signs improved. No recurrence has been observed for five months.