An analysis of the prognostic factors of acute myocardial infarction in different gender
10.3760/cma.j.issn.0578-1426.2009.02.014
- VernacularTitle:不同性别急性心肌梗死患者预后影响因素分析
- Author:
Chunmei WANG
;
Xuesi WU
;
Zhihong HAN
;
Qian ZHANG
- Publication Type:Journal Article
- Keywords:
Sex factors;
Myocardial infarction;
Prognosis
- From:
Chinese Journal of Internal Medicine
2009;48(2):126-129
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyse the prognostic factors of ST-elevation acute myocardial infarction men and women. Methods The data of 904 in-hospital patients with ST-elevation myocardial infarction were collected from the database of our hospital during 2003-2004 and 728 of them were followod-up. The patients were divided into groups of male and female. Results Women had more accompanying diseases such as diabetes mellitus (DM) and hypertension than men; left ventricular ejection fraction(LVEF) was lower in female. The rate of successful reperfusion was lower in women than men (P < 0.05). Mortality rate was higher in women. 728(202 female) patients were followed up. The use of β-blockers were statistically different between two groups during follow-up. In the female group, LVEF was lower significantly and the rate of reodmission for heart failure and myocardial infarction as well as that of mortality was higher (P< 0.05). Multivariate analysis showed that sex difference was an independent risk factor for in-hospital mortality (OR = 2. 130,95% CI 0. 954-4.754, P = 0. 045) , but not for mortality in the followed-up period and readrnission. Conclusion There are many factors leading to the poor prognosis of ST-elevation acute myocardial infarction in women. It is essential to pay more attention to its clinical characteristics and begin intervention of the risk factors earlier so as to improve the prognosis.
