Clinical study of serum C-reactive protein,supplement C3 and C4 in the patients with systemic inflammatory response syndrome induced by acute cerebral infarction
10.3760/cma.j.issn.1008-6315.2009.02.023
- VernacularTitle:急性脑梗死诱发全身炎症反应综合征患者血清C-反应蛋白和补体C3、C4水平变化
- Author:
Song WANG
;
Hongzhi GUO
- Publication Type:Journal Article
- Keywords:
Acute cerebral infarction;
Systemic inflammatory response syndrome;
C-reactive protein;
Supplement C3;
Supplement CA
- From:
Clinical Medicine of China
2009;25(2):167-169
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the role of serum C-reactive protein (CRP) ,supplement C3 and CA in sys-temic inflammatory response syndrome (SIRS) induced by acute cerebral infarction(ACI).Methods The levels of CRP,C3 and CA were measured by automatic immunoturbidimetry in 52 ACI cases accompanied with SIRS (SIRS group) ,50 cases of acute simple cerebral infarction(SACI group) and 46 normal cases (control group).Results The serum CRP, C3 ,and CA levels were significantly different among the three groups( F=720.6,580.8,94.1 ,P <0.01) ,the serum CRP levels in SIRS group were significantly higher than those in SACI group(P <0.01 ).The ser-um C3 and CA levels in SIRS were significantly lower than those in SACI group(P <0.01).With the diagnosis crite-rion items increasing, the serum CRP levels tended to be higher (t = 7.69 ,P < 0.01 ), and the serum C3, CA levels tended to be lower meeting SIRS diagnosis criterion numbers increasing respectively (t=10.68 and 10.53, P <0.01).Conclusion The serum ClIP levels are higher significantly and the serum levels of C3 and C4 are lower sig-nificantly when ACI progresses to SIRS.The serum CRP,C3,CA level changes can be used as an index for judging the progress of ACI progressed to SIRS.
