Improvement of abnormal calcium-phosphorus metabolism in hemodialysis patients
10.3760/cma.j.issn.1673-4904.2009.06.002
- VernacularTitle:对血液透析患者钙磷代谢异常改进治疗的研究
- Author:
Yinghui DENG
;
Jinglin WU
;
Wenjing FU
;
Qiang JIA
- Publication Type:Journal Article
- Keywords:
Renal dialysis;
Calcium;
Phosphorus;
Quality of life
- From:
Chinese Journal of Postgraduates of Medicine
2009;32(6):3-6
- CountryChina
- Language:Chinese
-
Abstract:
Objective To improve the treatment of abnormal calcium-phosphorus metabolism in hemodialysis patients, and observe its influence on the quality of life. Methods Implemented the kidney Disease Outcomes Quality Initiative (K/DOQI) clinical practice guidelines for bone metabolism and disease in hemodialysis patients, improved the treatment of abnormal calcium-phesphoms metabolism in hemodialysis patients. After 1 year, the values were compared between before and after application of K/DOQI guidelines, including albumin-adjusted serum calcium, phosphorus, calcium × phosphorus (Ca × P) product, and intact parathyroid hormone (iPTH) and their achieved target range rates. The quality of life were evaluated by using the kidney disease questionnaire (KDQ). Results One year later, the levels of serum calcium, phosphorus, Ca × P product, and iPTH were all decreased (P<0.01 or <0.05) compared with before the application of K/DOQI guidelines. The percentage of patients fell within the guideline range were as follows: 74.42% (32/43), calcium; 62.79%(27/43), phosphorus; 55.81%(24/43), Ca × P product; 60.47%(26/43), iPTH; 25.58%(11/43), all four criteria, higher than before (P<0.01 or <0.05). The scores of KDQ in global indices and symptom scores of physical symptoms, fatigue, depression, relationships with others and frustration dimension were also all increased (P<0.01). Conclusion The state of calcium-phospberns metabolism in hemodialysis patients is improved, the quality of life is also enhanced.
