Heart rate variability during intubation under etomidate or propofol general anesthesia with elderly coronary heart disease patients in non-cardinc surgery
10.3760/cma.j.issn.1673-4904.2009.06.008
- VernacularTitle:依托咪酯或丙泊酚对老年冠心病非心脏手术围插管期心率变异性的影响
- Author:
Haihui XIE
;
Shu ZHANG
;
Haiyan SHI
;
Miao CHEN
;
Ye TU
- Publication Type:Journal Article
- Keywords:
Propofol;
Coronary arteriosclerosis;
Etomidate;
Heart rate variability
- From:
Chinese Journal of Postgraduates of Medicine
2009;32(6):19-21
- CountryChina
- Language:Chinese
-
Abstract:
Objective To research etomidate or propofol in the whole intubation during the induction of elderly coronary heart disease autonomic nervous system function. Methods Ninety patients undergoing abdominal surgery patients with coronary heart disease were randomly divided into etomidate group (E group, 45 cases) and propofol group (P group, 45 cases). In pre-anesthesia, after the induction of anesthesia and after intubatiou with power spectral analysis of heart rate variability (HRPSA) observed in patients with heart rate variability (HRV) changes. Results After the induction of anesthesia, the low frequency(LF)[(316±301) ms2/Hz] end total power(TP)[(756±535) ms2/Hz] decreased significantly in E group(P<0.05) and LF, high frequency (HF), LF/HF ratio(LF/HF)and TP decreased significantly in P group [ (187±168) ms2/Hz, (89±48)ms2/Hz, 2.3±1.6 and (616±462) ms2/Hz] (P<0.05). The duction degree of LF, HF, TP and LF/HF in E group was more significant than that in P group (P<0.05). After intubation, LF, HF, LF/HF and TP increased significantly in both groups and no significant difference of HRV was observed between the two groups (P>0.05). Conclusions Propofol decreases the activity of autonomic nervous system, wherea etomidate produces minimal changes under anesthesia induction in elderly coronary heart disease patients.There is no remarkable difference in cardiovasological changes induced by etomidate and propofol during tracheal intubation.
