The effect on leukocytes in peripheral blood and C-reactive protein levels after eradication of Helicobacter pylori
- VernacularTitle:根除幽门螺杆菌对外周血白细胞和C-反应蛋白的影响
- Author:
Renxu LAI
;
Lei MAI
;
Xianqi LIN
;
Hongjiang CHEN
;
Huixue GUO
- Publication Type:Journal Article
- Keywords:
Helicobacter pylori;
Leukecytes;
C-reactive protein
- From:
Chinese Journal of Postgraduates of Medicine
2008;31(z1):28-31
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the systemic effects of Helicobacter pylori (Hp) infection by comparing differential counts of leukocytes in peripheral blood and C-reactive protein (CRP) levels before and after eradication of Hp. Method A total of 158 Hp-positive patients underwent eradication by standard one-week triple therapy were divided into Hp eradicated group(n = 108) and Hp non-eradicated group(n = 50),the populations of peripheral blood leukocytes and CRP levels before and 0 (just after therapy),1 and 12 months after eradication were retrospectively analysed. Results In the eradicated group,blood leukecytes,neutrophils and monocytes decreased significantly after eradication,and the CRP levels were significantly lower than the levels before treatment (P < 0.05 ),but there was no significant change in eosinophils,basophils and lymphecytes (P > 0.05).In the non-eradicated group,there was no significant change in any studied pa-rameter (P > 0.05). Conclusion These findings suggest that Hp infection increase blood leukocytes,neu-trophil and monocyte counts in the peripheral blood and CRP levels,which indicates a significant role of Hp infection in systemic disorders.
