Effect of fleabane injection on serum D-dimer, fibrinogen and hypersensitive C-reactive protein in patients with IgA nephropathy
- VernacularTitle:灯盏细辛注射液对IgA肾病患者血D-二聚体、纤维蛋白原、超敏C-反应蛋白的影响
- Author:
Hongtao CHEN
;
Huili XU
;
Yi XU
;
Shaodong LUAN
;
Qijun WAN
;
Yongcheng HE
;
Quanying LIU
- Publication Type:Journal Article
- Keywords:
IgA Nephropathy;
Fleabane Injection;
D-dimer;
Fibrinogen;
Hypersensitive C-reactive protein
- From:
Clinical Medicine of China
2008;24(z1):6-8
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of fleabane injection on serum level of D-dimer, fibrinogen and hypersensitive C-reactive protein in patients with IgA nephropathy and to explore the mechanism of fleabane injection for treating IgA nephropathy. Methods 29 patients with IgA nephropathy were given fleabane injection together with routine treatment. Another group of 28 patients with IgA nephropathy were only treated with routine treatment as con-trol. Determinations of 24 hours urine protein output(24HPQ), serum level of D-dimer(D-D), Fibrinogen(Fib) and hypersensitive C-reactive protein (hsCRP) were carried out pre- and post-study. Results Significant decrease in 24HPQ , serum level of D-D, Fib and hsCRP were observed in both treatment group and control group(P <0. 01 ～0. 05), but more significant in treatment group as compared with control group ( P < 0. 05). Conclusion Flea-bane Injection plus routine treatment could significantly decrease 24HPQ in patients with IgA nephropathy, and this maybe contribute to regulation of D-D, Fib and hsCRP by fleabane injection.
