Effect of different treatment methods on left ventricular remodeling after acute myocardial infarction

VernacularTitle:卡托普利联合美托洛尔治疗对改善急性心肌梗死后左心室重构的作用
Author: Xiaoling PENG
Publication Type:Journal Article
Keywords: Myocardial infarction; Ventricular remodeling; Captopril; Metoprolol
From: Chinese Journal of Primary Medicine and Pharmacy 2009;16(2):213-214
CountryChina
Language:Chinese
Abstract: Objective To study the effect of captopril combined with metoprolol and captopril alone on improving left ventricular remodeling(LVR)in acute myocardial infarction(AMI).Methods 100 AMI patients were randomly divided into treatment group of 50 cases(captopril combined metoprolol treatment)and 50 cases in the control group(captopril treatment).Using color Doppler ultrasound to deteimine left ventricular shape,configuration and indicators to compare two groups left ventricular remodeling after early(＜2gh);3;6 month end.Results The indices of RaPD;ASL in control group after 6 months end[(63.01±4.10)%and(10.69 ±1.8)cm]were higher than the treatment group[(60.91±3.21)and(10.69±1.8)cm](t=2.121;2.210,all P＜0.05);The LVEF in treatment group after 6 months(51.10±4.60)%were higher than the treatment group(49.10±5,10)%(t=2.231,P＜0.05).Conclusion The captopril combined metoprolol on left ventricular remodeling inhibition significantly better than captopril alone in AMI.