Hyperglycemia and stroke
10.3760/cma.j.issn.1673-4165.2009.01.009
- VernacularTitle:高血糖与卒中
- Author:
Li ZHANG
;
Yansheng LI
- Publication Type:Journal Article
- Keywords:
hyperglycemia;
stroke;
diabetes mellitus
- From:
International Journal of Cerebrovascular Diseases
2009;17(1):37-40
- CountryChina
- Language:Chinese
-
Abstract:
Hyperglycemia has direct and indirect impact on the occurrence and develop-ment of stroke. At present, hyperglycemia is considered as an independent risk factor for stroke. Hyperglycemia directly involves in cellular and vascular injury through activating polyol pathway, forming advanced glycosylation end product, activating protein kinase C and the hexosamine pathway. Moreover, hyperglycemia involves in vascular injury through the indirectly pathway such as lipid metabolism, glycosylated hemoglobin and insulin. Controlling hyperglycemia may effectively reduce the incidence of stroke and improve the prognosis in patients with stroke.
