Mechanisms of vascular endothelial cadherin involved in atherosclerosis
10.3760/cma.j.issn.1673-4165.2009.01.013
- VernacularTitle:血管内皮钙黏蛋白参与动脉粥样硬化形成的机制
- Author:
Yanlin ZHANG
;
Yongjun CAO
;
Chunfeng LIU
- Publication Type:Journal Article
- Keywords:
vascular endothelial cadherin;
atherosclerosis;
cell troliferation;
apoptosis;
angiogenesis
- From:
International Journal of Cerebrovascular Diseases
2009;17(1):53-56
- CountryChina
- Language:Chinese
-
Abstract:
As a major adhesion molecule of endothelial junction, vascular endothelial cadherin (VE-cadherin) plays a very important role for the maintenance of vascular homeostasis. It regulates infiltration of vascular endothelia on contents in plasma such as eukocytes and lipid, as well as cellular proliferation and apoptosis. It plays an important role by involving in angiogenesis in the multiple links of the process of atherosclerosis, This article reviews the recent progress in research on the effects and mechanisms of VE-cadherin in the occurrence and developmaent of atherosclerosis in recent years.
