Application of a new mismatch model on evaluating infarct core and penumbra in acute ischemic stroke using CT perfusion source images
10.3760/cma.j.issn.1005-1201.2009.03.002
- VernacularTitle:CT灌注原始图像不匹配模型评价急性缺血性脑卒中缺血半暗带和梗死核心的价值
- Author:
Xiaochun WANG
;
Peiyi GAO
;
Jing XUE
;
Guangrui LIU
;
Li MA
;
Chen WANG
- Publication Type:Journal Article
- Keywords:
Cerebrovascular accident;
Tomography,X-ray computed;
Perfusion
- From:
Chinese Journal of Radiology
2009;43(3):231-234
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the diagnostic value of determining infarct core and penumbra using CT perfusion source images (CTP-SI) mismatch model in hemispheric stroke less than 9 hours.Methods "one-stop shop" CT examination including non-contrast enhanced CT (NCCT), CTP, CT angiography (CTA) were performed in 24 patients with symptoms of stroke less than 9 hours.The Alberta Stroke Program Early CT Score (ASPECTS) were analyzed on arterial phase CTP-SI and venous phase CTP SI using Wilcoxon rank-sum test, then compared with the follow up imaging ASPECTS using multiple linear regression.Results The median (min-max) scores of ASPECTS on arterial phase CTP-SI, venous phase CTP-SI and follow-up imaging were 9.0 ( 2.0-10.0 ), 9.3 ( 6.5-10.0 ) and 9.0 ( 7.0-10.0 ),respectively. ASPECTS measured on arterial phase CTP-SI significantly differed from the ASPECTS on venous phase CTP-SI ( Z =-2.812, P = 0.005 ).Moreover, the linear regression analysis showed significant correlation between the ASPECTS on venous phase CTP-SI and follow up imaging ASPECTS ( Beta =0.715,P = 0.003 ).Conclusion CTP-SI mismatch model provides a method of choice in predicting penumbra and infarct core in hemispheric stroke.
