Impact of different graded coronary stenosis on myocardial perfnsion and function by two-dimensional strain echocardiography combined with myocardial contrast echocardiography
10.3760/cma.j.issn.1004-4477.2009.02.008
- VernacularTitle:二维应变超声心动图结合实时心肌超声造影评价冠状动脉不同狭窄程度对心肌灌注和心功能的影响
- Author:
Yan LI
;
Qing Lü
;
Jing WANG
;
Yanrong ZHANG
;
Ming CHEN
;
Jing ZHANG
;
Lingyun FANG
- Publication Type:Journal Article
- Keywords:
Echocardiography;
Microbubbles;
Coronary stenosis;
Ventricular function
- From:
Chinese Journal of Ultrasonography
2009;18(2):118-121
- CountryChina
- Language:Chinese
-
Abstract:
Objective To estimate the impact of various extent of coronary stenosis at rest on myocardial perfusion and functional indices from myocardial contrast echocardiography(MCE) and two-dimensional strain echocardiography(2D-Strain) and characterize the relationship between them. Methods Three levels of coronary stenosis:mild (50%～75%),moderate (76%～89%),severe (≥90%) in 25 patients with coronary artery stenosis and 15 healthy subjects in the control group were examined. Plateau videointensity (value A) and time to plateau (value β) of the replenishment curve from MCE were calculated for perfusion analysis,and longitudinal peak systolic strain(SL) from 2D-Strain were measured for functional analysis. Results Value A tended to decrease with increasing severity of stenosis,ahhough these differences did not reach the level of statistical significance, β and SL were significantly increased in the context of moderate and severe coronary stenosis when compared with control group (β, moderate 0.75±0.67 and severe 0.67±0.53 vs normal 0.97±0.65;SL,moderate 11.60±5.89 and severe 9.58±6.51 vs normal 19.46±6.17, P <0.05, respectively). β was positively correlated with SL (r = 0.65, P <0.05).Conclusions β of the replenishment curve from MCE and SL from 2D-Strain both can detect greater than 75% coronary stenosis inducing myocardial ischemia,and they had good correlation.
