Comparison of two subcutaneous insulin regimens in type 2 diabetic patients with fractures during perioperative period

VernacularTitle:两种胰岛素治疗方案对2型糖尿病患者骨折围手术期效果的比较
Author: Wei DENG ; Linong JI ; Bosong ZHANG ; Guoying ZHANG ; Lili HUO
Publication Type:Journal Article
Keywords: Diabetes mellitus; Intraoperative period
From: Chinese Journal of General Practitioners 2009;8(3):194-196
CountryChina
Language:Chinese
Abstract: We compare the results of two subcutaneous insulin regimens in type 2 diabetic patients with fractures during the perioperative period. In group Ⅰ 162 patients received regular insulin three times+ NPH insulin bedtime protocol; in group Ⅱ 72 patients received regular insulin three times + NPH insulin twice protocol. The difference of the time achieving satisfactory level of blood glucose (BG) and associated factors were analyzed, and the related complications were observed. The average time achieving satisfactory BG level was (9.1±3. 3) days and (7.0±2.6) days for group Ⅰ and Ⅱ respectively (P <0.05). There were no statistical differences in hypoglycemia, infection and thrombosis between two groups. Binary logistics regression showed that the time of achieving desired BG level was associated with blood glucose(BG) and the proportion of the regular insulin and the NPH. The results indicate that five times insulin injection method can shorten the time of achieving desired BG level and may be benefit to diabetic patients with fracture.