Comparison of 16-slice spiral CT and MMP-9 in diagnosis of invasion and metastasis in hman esophageal cancer
- VernacularTitle:螺旋CT和基质金属蛋白酶-9诊断食管癌浸润和转移的价值比较
- Author:
Hongyuan WANG
;
Lin SUI
- Publication Type:Journal Article
- Keywords:
Esophageal neoplasms;
Tomography;
X-ray computed;
Matrix metalloproteinase-9
- From:
Chinese Journal of Primary Medicine and Pharmacy
2008;15(8):1337-1338
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the clinical values of 16-slice spiral coroputed tomography(CT)and matrix metalloproteinases-9(MMP-9)in diagnosis of invasion and metastasis in human esophageal cancer.Methods Thirty-eight patients with esophageal cancer were detected with spiral CT,and their tumor tissues were detected for expression of MMP-9.Results 12 cases were diagnosed for vicinitic tissues damages by histopathological examination,while 11 cases were regarded to be damaged by CT and 13 cases were done according to MMP-9 determination;as to metastasis,there were 13 casese by histopathological examination,12 cases by CT and 16 cascs by MMP-9 determination.No statistical difference were observed in diagnosis of vicinitic tissues damages and metastasis by the three methods in positive rates,sensitivity,accuracy,specificity and diagnosis accordance rates(P＞0.05).Conclusion It is the important method for spiral CT in diagnosis of esophageal cancer,which could not be replaced by others in judgement of invasion and metastasis.
