The level of GITR mRNA expression on peripheral blood monocytes of patients with primary biliary cirrhosis
- VernacularTitle:原发性胆汁性肝硬化患者外周血单个核细胞中糖皮质激素诱导的肿瘤坏死因子受体mRNA表达水平的研究
- Author:
Dawei TONG
;
Yang ZHANG
;
Yongzhe LI
;
Hongmei WANG
;
Guanfei ZHAO
;
Xue FENG
;
Shumeng BAO
;
Shulan ZHANG
;
Chaojun HU
- Publication Type:Journal Article
- From:
Chinese Journal of Rheumatology
2008;12(11):765-767
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect the expression of GITR mRNA in peripheral blood mononuclear cells (PBMCs) of patients with primary biliary cirrhosis (PBC) and its relationship with the disease activity of PBC.Methods Real time quantitative reverse transcription polymerase chain reaction (FQ-RT-PCR) was used to examine GITR mRNA expression on peripheral blood monocytes of 44 active PBC, 34 stable PBC, 30.hepa-toma cases and 30 healthy controls. Results The mean GITR mRNA expression of active PBC (△Ct=10.5±
