A application study of dose constraint template in intensity modulated radiation therapy planning for early stage nasopharyngeal carcinoma
10.3760/cma.j.issn.0254-5098.2009.01.019
- VernacularTitle:剂量限制模板在早期鼻咽癌调强放疗计划中的应用研究
- Author:
Wei HU
;
Changhui YU
;
Minghai SHAO
;
Haihua YANG
;
Weijun DING
;
Weifang YANG
;
Guoping SHAN
;
Shixiu WU
- Publication Type:Journal Article
- Keywords:
Nasopharyngeal neoplasm;
Radiotherapy;
Intensity modulated;
Dose constraint;
Dose template
- From:
Chinese Journal of Radiological Medicine and Protection
2009;29(1):61-64
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate a feasibility of using dose constraint template (DCT) to increase conformity index (CI) of planning target volume (PTV) and improve intensity modulated radiation therapy (IMRT) planning efficiency for early stage nasopharyngeal carcinoma. Methods Ten patients with pathological diagnosed and treated by IMRT were selected for this study. Target volumes were delineated with Corvus 6.3 of treatment planning system, two dose limiting regions(DLR) around PIN were added by extending from PIN,each DLR was 1 cm thick. We created three plans:Plan0,Planl and Plan2. PianO was without DLR and DCT, Planl without DLR but with DCT, Plan2 with both condition;but to compare dose distribution in PLTV and normal tissue using three plans. Results Three plans could fill equal request of dose distribution in PLTV and normal tissue, and their difference was not statistical significant. CI of Plan2 was increased and planning time was decreased significantly compared with Piano and Planl. Conclusloa Usage of DCT together with DLR can increase CI of PTV and improve IMRT planning efficiency for early stage nasopharyngeal carcinoma, planning time is shortened significantly.