The imaging findings of metastatic neuroblastoma in the craniofacial bone in children
10.3760/cma.j.issn.1005-1201.2009.03.008
- VernacularTitle:儿童神经母细胞瘤颅面骨转移的影像表现
- Author:
Xin BIAN
;
Zhenchang WANG
;
Junfang XIAN
;
Mei LI
;
Fei YAN
;
Qinghua CHEN
;
Bentao YANG
;
Qinglin CHANG
;
Qichang TIAN
;
Zhonglin LIU
- Publication Type:Journal Article
- Keywords:
Neuroblastoma;
Head and neck neoplasms;
Diagnostic imaging;
Child;
Neoplasm metastasis
- From:
Chinese Journal of Radiology
2009;43(3):258-261
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the characteristic imaging findings of metastatic neuroblastoma in the craniofacial bone in children. Methods Imaging findings in 12 patients with metastatic neuroblastoma in the craniofacial bone were analyzed retrospectively. Among them, 10 patients underwent plain CT scan, 6 underwent MRI and 7 underwent whole body single-photon emission computed tomography bone scanning.Results In the 10 patients with CT images, lytic bone destruction and soft tissue masses were found in 9 cases, in which periosteal reaction was observed in 8 patients with spiculated periosteal reaction in 3 patients.The remaining 1 patient didn't show any abnormalities on CT images but had abnormal findings in bone scanning.Six patients with MR images showed abnormal signal intensity in the bone marrow of the craniofacial bone and adjacent soft tissue masses. Postcontrast T1-weighted imaging in 5 patients demonstrated remarkable enhancement of the bone marrow and soft tissue masses. Bone scanning of 7 patients showed abnormal foci of increased radionuclide activity of the craniofacial bone in 7 patients and metastasis at other body parts in 6 patients.Conclusion The metastatic neuroblastoma in the craniofacial bone has its characteristic imaging findings which are helpful for correct diagnosis.
