The application of multi-modal MRI in venous thrombolysis therapy for hyperacute cerebral arterial thrombosis
10.3760/cma.j.issn.1005-1201.2009.03.004
- VernacularTitle:多模式MRI指导的超急性期缺血性脑卒中静脉溶栓治疗
- Author:
Zhenguo ZHAO
;
Qingke BAI
;
Haijing SUI
;
Xiuhai XIE
;
Xiaohui ZHAO
;
Lianwen WANG
;
Weiying XIA
;
Lianjun LU
;
Jian SHEN
;
Yuan ZHOU
;
Juan CHEN
;
Cuirong CHEN
;
Jinshi LI
- Publication Type:Journal Article
- Keywords:
Cerebmvascular accident;
Thrombolytic therapy;
Magnetic regonance imaging
- From:
Chinese Journal of Radiology
2009;43(3):239-243
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of MRI in thmmbolytic thempy of hyperacute cerebral arterial thrombosis.Methods One hundred and sixteen patients with acute cerebral arterial thrombosis were recruited.plain CT and multi.modal MRI were performed in all patients.Thirty-three patients with hyperacute cerebral infarction were treated bv recombinant tissue plasminogen activator(rt-PA) and followed-up periodically using MRI.Results The 33 patients with thrombolysis selected by MRI demonstrated clinical improvement.90 d moclified Rankin scale scores(mRs)were less than 2 and life quality Barthal indexes(BI)were from 80 to 100.The complication included one asymptomatic parenchymal hematoma(PH1)one weeks after thrombolytic therapy and 4(12.2%)hemorrhagic infarction(HI)6 to 24 hours after thrombolytic therapy.Condusions MRI has significant clinical value for the screening and follow-up of intravenous thrombolytic therapy of hyperacute ischemic stroke.MRI-based thrombolysis is a safe and effective method for hyperacute ischemic stroke.
