The Effects of Atropine and Glycopyrrolate mixed to Neostigmine on Heart Rate in Anesthetized Pediatric Patients .
10.4097/kjae.1988.21.4.564
- Author:
Keung Sook LEE
1
;
Dae Pal PARK
Author Information
1. Department of Anesthesiology, Yeungnam University, College of Medicine, Taegu, Korea.
- Publication Type:Original Article
- Keywords:
Pediatric patients;
Neostigmine;
Glycopyrrolate;
Atropine;
Heart rate;
Neuromuscular blocker
- MeSH:
Anesthesia;
Atropine*;
Glycopyrrolate*;
Heart Rate*;
Heart*;
Humans;
Neostigmine*;
Relaxation
- From:Korean Journal of Anesthesiology
1988;21(4):564-568
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Fourty pediatric patients anesthetized with halothane-nitrous oxide-oxygen, who received pancronium for the maintenance of muscular relaxation, were divided into two groups. On anesthesia, in group l, atropine(20ug/kg) and neostigmin(40ug/kg), and in group ll, glycopyrrolate(10ug/kg) and neostigmine(40ug/kg) were injected transvenously. The changes in heart rate and arrythmis were then observed. The results were as follows: 1) The safety and effectiveness of both groups in antagonizing the muscarinic actions of neostigmine were demonstrated. 2) Glycopyrrolate produced a significantly smaller change in heart rate than atropine. 3) In both groups, arrhythmis could not be observed.
