Mechanisms of perihematoma tissue injury after intracerebral hemorrhage

VernacularTitle:脑出血后血肿周围组织损伤的机制
Author: Hui CHEN ; Kaifu KE
Publication Type:Journal Article
Keywords: intracerebral hemorrhage; brain injury
From: International Journal of Cerebrovascular Diseases 2009;17(2):110-114
CountryChina
Language:Chinese
Abstract: The morbidity and mortality of intracerebral hemorrhage (ICH) are very high. Brain injury involves in several mechanisms after ICH, including the direct tissue destruction by the mechanical force on brain tissue surrounding the hernatoma in the process of hematoma formation, the release of clot-derived factors (thrombin, hemoglobin degradation products), inflammatory response and complement cascade reaction, etc. This article reviews the above mechanisms