Pharmacological mechanisms and clinical application of mannitol in intracerebral hemorrhage
10.3760/cma.j.issn.1673-4165.2009.02.007
- VernacularTitle:甘露醇治疗脑出血的药理学机制和临床应用
- Author:
Hongxia NIE
;
Yousong YANG
- Publication Type:Journal Article
- Keywords:
mannitol;
intracerebral hemorrhage;
pharmacological processes;
clinical application
- From:
International Journal of Cerebrovascular Diseases
2009;17(2):115-117
- CountryChina
- Language:Chinese
-
Abstract:
One of the important therapeutic measures in the acute stage of cerebral hemorrhage is to treat cerebral edema and lower intracranial pressure. Mannitol, an osmotic dehydrant, is most widely used in clinical practice. Its major effects include the reduction of intracranial pressure and cerebral edema and prevention of cerebral herniation. Besides, mannitol scavenges oxygen free radicals and protects brain cells. So it has extremely important significance in reducing the mortality of intracerebral hemorrhage.
