The role of Scleraxis and Tenomodulin in tendon development
- VernacularTitle:Scleraxis和Tenomodulin在肌腱发育成熟中的作用
- Author:
Yongkang JIANG
;
Wei LIU
- Publication Type:Journal Article
- Keywords:
Tendon;
Development;
Scleraxisi;
Tenomodulin
- From:
International Journal of Biomedical Engineering
2008;31(6):365-368
- CountryChina
- Language:Chinese
-
Abstract:
Tendons are dense connective tissues that mediate the attachment of the muscle system to the skeletal system. While the methods for clinical tendon repair remain less satisfactory, tissue engineering may pro- vide promising future. Therefore, understanding the natural tendon development process is important for tendon en- gineering. Scleraxis and Tenomodulin are relatively specific molecule makers for tendon and ligment and play im- portant roles in the tendon development. This article gives review of the molecular structure, the expression regula- tion, and the roles of Scleraxis and Tenomodulin in tendon development, in order to better understand the process of tendon development.