Tolterodine to prevent and treat bladder spasm around the operation to BPH
- VernacularTitle:托特罗定防治良性前列腺增生患者围手术期膀胱痉挛的临床疗效
- Author:
Ran TAO
;
Songqiang PANG
;
Jin LIU
- Publication Type:Journal Article
- Keywords:
Benign prostatic hyperplasia;
Tolterodine;
Bladder spasm
- From:
Chinese Journal of Urology
2008;29(12):843-845
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of tolterodine in preventing bladder spasm during the operation to BPH.Methods One hundred and twelve cases of BPH patients were randomized to two groups:56 cases in one group were prescribed tolterodine 4-5 d before operation and 3-4 d after operation (2 mg twice daily),another 56 cases did not take any anti-spasm drugs.The bladder spasm occurring or not,frequency and continuing time of bladder were evaluated and recorded.Results In the controlling group:the non bladder spasm in 12.5% (7/56),mild bladder spasm in 14.3% (8/56),severe bladder spasm in 73.3% (41/56),In the treatment group:non bladder spasm in 87.5% (49/ 56),mild bladder spasm in 8.9% (5/56),severe bladder spasm in 3.6% (2/56).There was signifi-cant difference between the 2 groups (P<0.001).Conclusion Tolterodine could alleviate bladder spasm around the operation to BPH.
