Clinical aralysis of the increase in full three-dimensional conformal radiotherapy for esophageal cancer

VernacularTitle:全程三维适形加量放疗治疗食管癌临床分析
Author: Hongsheng LI ; Yonglu MA ; Yue LIU
Publication Type:Journal Article
Keywords: Esophageal neoplasms; Radiotherapy,Conformal
From: Chinese Journal of Primary Medicine and Pharmacy 2009;16(3):400-401
CountryChina
Language:Chinese
Abstract: Objective To evaluate the effct of full increase of three-dimensional conformal radiotherapy on esophageal carcinoma.Methods 86 Esophageal cancer patients which has been pathologically confirmed were randomly divided into study group and control group.The control group showed in tumor invasion scope simulator under barium meal positioning,with three fields outside irradiation;Total dose of DT with 63～70 Gy,35 times,seven weeks to complete.Study group showed that full use of additional 3D treatment planning system design individualized treatment programs,90% of the dose contains all planned target volume,future confonnal irradiation DY 44～50 Gy,after the wild-shrinkage increases to a total dose DT66～75 Gy,30 times,completed six weeks.Results The study group and the control group after radiotherapy in a local control rates were 86.4%and 64.3%(x2=4.5420,P＜0.05).Overall response rate(CR+PR)in two group were 93.2%and 76.2%(x2=3.6014,P=0.0577).Two toxicity of the difference was not significant.Conclusion The increase in full three-dimensional conformal radiotherapy of esophageal emleer in the near future is better than conventional methods.