Three dimensional conformal radiotherapy combined with chemotherapy for locally advanced non-small cell lung cancer

VernacularTitle:三维适形放疗配合化疗治疗晚期非小细胞肺癌的临床研究
Author: Difei DING ; Kai HU ; Zhaoding SU ; Yusheng WANG ; Jingsong SHU
Publication Type:Journal Article
Keywords: Carcinoma,non-small-cell lung; Radiotherapy,conformal; Chemotherapy
From: Chinese Journal of Primary Medicine and Pharmacy 2009;16(3):443-444
CountryChina
Language:Chinese
Abstract: Objective To evaluate the acute side effects and efficacy of three dimensional conformal radiotherapy(3DCRT)combined with chemotherapy(CT)for locally advance non-small cell lung cancer(NSCLC).Methods from May.2002 tO Dec 2004,36 patients with NSCLC were treated with three dimensional-conformal radiotherapy combined with chemotherapy navelbine+cisplafin(NP)Results The overall response rate(CR+PR)was 91.7% for the primary tumor,and 100%for metastases mediastinal lymph mode.The leucopenia mte was 94.4%(55.6%Grade 3.4)Acute radiation esophagitis occurred in 52.8%of patients(Grade 1.2)Acute radiation pneumonitis was observed in 11.1%of patients(Grade 1.2)Conclusion 3DCRT combined with CT is well tolerated in most patients with NSCLC.Its early responses are milder than the conventional radiotherapy combined with chemotherapy.Remote results awmt further follow-up