Analysis of four cases of folliculotropic mycosis fungoides

VernacularTitle:亲毛囊性蕈样肉芽肿四例分析
Author: Kun CHEN ; Yiqun JIANG ; Chengrang LI ; Juanqin GONG ; Heng GU ; Baozhu CHANG
Publication Type:Journal Article
Keywords: Mycosis fungoides; Hair follicle; Lymphoma,T-cell
From: Chinese Journal of Dermatology 2009;42(4):230-233
CountryChina
Language:Chinese
Abstract: Here four cases of folliculotropic mycosis fungoides are reported.Of these patients,one was a female and three were males with the age varying from 32 to 52 vears.Three patients presented with multiple,densely distributed,irregularly shaped,dark red infiltrated plaques,nodules,tumors,follicular papules and acneiform lesions preferentially distributed on the head and neck,as well as patches and mildly infiltrated plaques.foilicular papules and aeneifotin lesions on the trunk and extremities.One patient presented with follicular papules all over the bodv with the exception of head and face.Characteristic findings of histopathology included massive lymphoid cell infiltration.heteromorphism of some cells and migration of infiltrated cells into follicular epithelium.No typical epidermotropism was noticed.Two cases showed mnciprotein deposition in follicular epithelium,which was positive for alcian blue staining.The infiltrates were predominated bv CD4+ T lymphocytes.Folliculotropic mycosis fungoides is a refractory disense with poor response to conventional therapy of classical mycosis fungoides.Relapse is common in patients with partial remission.