Relationship between carotid atherosclerotic plaque and its related factors and ischemic cerebrovascular disease
10.3760/cma.j.issn.1008-6706.2009.03.052
- VernacularTitle:颈动脉硬化斑块及其相关因素与缺血性脑血管病的关系
- Author:
Chuanqing YU
;
Mei ZHANG
;
Min XUE
- Publication Type:Journal Article
- Keywords:
Cerebrovascular accident;
Arteriosclerosis;
C-reactive protein;
Homocysteine
- From:
Chinese Journal of Primary Medicine and Pharmacy
2009;16(3):482-483
- CountryChina
- Language:Chinese
-
Abstract:
Objeclive To investigate the relationship between carotid atheroselemtic(CAS)plaque and homocysteine(HCY),C-reactive protein(CRP)and ischemie eerebrovasclar desease(ICVD).Methods 468 patients with ICVD and 456 patients without eerebrovaseular disease(control group)were detected by carotid color duplex in IMI,number,size and character of carotid atherosclerosis(CAS) plaque and thelevels of HCY and CRP were evaluated,and compared with normal control group.Results(1)Compare with control group,the IMT,prevalence of CAS plaque,the rates of soft plaque in ICVD group were significantly higher(all P＜0.05).(2)The levels of HCY and CRP in ICVD were significantly higher than those in control group(P＜0.05),and in ICVD with plaque subgroup were significantly higher than those in ICVD without plaque subgroup(P＜0.05).(3)The prevalence of CAS plaque and IMT were positively correlated with the levels of HCY and CRP(r=0.32,0.30 repectively,P＜0.05).Condusion ICVD patients show increased IMT and hJish prevalence of CAS plaque.CAS plaque and hyperhomocystoinemia is an independent risk factor for ICVD.The level of CRP is an important biological marker to evaluate the severity and prognosis of ICVD.
