Effect of pregnant outcome in women with antiphospholipid syndrome
10.3760/cma.j.issn.1008-6706.2009.03.042
- VernacularTitle:妊娠合并抗磷脂综合征对妊娠结局的影响
- Author:
Ke PENG
;
Weihua YANG
;
Furong FANG
- Publication Type:Journal Article
- Keywords:
Anfiphospholipid syndrome;
Antiphospholipid antibody;
Heparin;
Aspirin
- From:
Chinese Journal of Primary Medicine and Pharmacy
2009;16(3):465-467
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy to pregnant outcoule with antieardiolipin antibody(ACA) of qualitative and quantitative before treatment and after treatment in women pregnant with antiphospho-lipid syndrome (APS).Methods The heparin combined with aspirin therapy APS 40 patients before and after treatment to momtor the change of ACAIgG,IgM.Results 40 patients were treated 37 eases of live births,success rate were92.5%,the rate of pregnancy loss were3 cases(7.5%);The lever of ACA-IgG and ACA-IgM were(67.63±2.53)u and (49.40±3.64)u beforetreatment andlever of ACA-IgG and ACA-IgM were(23.87±1.54)u and(21.60±2.59)u after treatment.The lever after treatment were significandy Iower than the before treatment(P＜0.01);The level of ACA were overall downward in 40 cases after treatment by dynamic observation;The rate of positive in ACAIgG (40.0)% after treatment lower than before treatment(52.5)%(X2=3.85,P＜0.05);The rate of positive in ACA IgM(37.5)% after treatment lower than before treatment(47.5)%(X2=3.81,P＜0.05).Conclusion Hepfinar treatment combined with aspirinmay be a safe and effective method for patients with APS.
