Pancreatic and renal involvement in von Hippel-Lindau disease: imaging findings
10.3760/cma.j.issn.1005-1201.2009.04.011
- VernacularTitle:von Hippel-Lindau病胰腺和肾受累的影像表现
- Author:
Canhui SUN
;
Shiting FENG
;
Zhenpeng PENG
;
Miao FAN
;
Huanyi GUO
;
Ziping LI
;
Quanfei MENG
- Publication Type:Journal Article
- Keywords:
van Hippel-Lindau disease;
Tomography,X-ray computed;
Magnetic resonanceimaging;
Kidney neoplasms;
Pancreatic neoplasms
- From:
Chinese Journal of Radiology
2009;43(4):378-381
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the imaging features and to enhance the understanding of pancreatic and renal involvement in yon Hippel-Lindau disease (VHLD). Methods CT and MRI appearances and clinical data of six patients with pancreatic and renal involvement in VHLD were studied retrospectively.Six patients underwent CT scanning, and two of them also had MRI.Results Pancreatic cysts found in all six patients varied from several small cysts to cystic replacement of the entire gland.Calcifications were detected in four patients. Multiple bilateral renal lesions were detected in six patients.The renal lesions were classified as cystic, cystic with solid components and solid.Multiple combined renal lesions were found in five patients, and multiple simple cysts in one patient.Unilateral nephrectomy was performed in two patients, and the renal masses were diagnosed as clear cell carcinoma by pathology.Bile carcinoid was found in one patient, and retroperitoneal metastasis in another.Conclusion Multiple pancreatic cysts and/or multiple and bilateral combined renal lesions are highly suggestive of VHLD.
