Analysis of influencing factors for postoperative adjuvant chemotherapy effects in elderly patients with breast cancer
10.3760/cma.j.issn.0254-9026.2009.04.011
- VernacularTitle:乳腺癌患者接受术后辅助化疗的影响因素分析
- Author:
Chuandong MA
;
Xiaosong CHEN
;
Guangyu LIU
;
Genhong DI
;
Jiong WU
;
Jinsong LU
;
Wentao YANG
;
Qixia HAN
;
Zhimin SHAO
;
Zhenzhou SHEN
;
Kunwei SHEN
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Chemotherapy,adjuvant
- From:
Chinese Journal of Geriatrics
2009;28(4):290-293
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influencing factors for postoperative adjuvant chemotherapy effects in elderly patients with breast cancer. Methods Five hundred and ninety female patients aged 65 years or older with invasive breast cancer were treated in our hospital, and the influencing factors for postoperative adjuvant chemotherapy effects were analyzed by chi-square test and logistic regression. Results Two hundred and thirty-one (39.2%) patients received postoperative adjuvant chemotherapy. The results showed that diabetes, age, patterns of operation and pathological characteristics of tumor had significant influences on postoperative adjuvant chemotherapy effects (χ2=4.49,88. 27,23.49 and 9.40, all P<0.05). Logistic regression analysis showed that age, tumor size, lymph node status(pN) and estrogen receptor (ER) status were related to postoperative adjuvant chemotherapy effects(χ2=68.857,15. 284,43. 540 and 7.009 ,all P<0.01). Forty-four patients (66.7%) with pN(+)/ER(-) received adjuvant chemotherapy. Conclusions Age, tumor size, lymph node status and ER status were independent predictive factors for postoperative adjuvant chemotherapy effects in elderly patients with breast cancer.
