The relationship between metabolic syndrome and nonalcoholic fatty liver disease in non-obese hypertensive patients
- VernacularTitle:非肥胖的高血压病患者的非酒精性脂肪肝与代谢综合征的关系
- Author:
Ying LU
;
Yanxa HUANG
;
Xiaomei LI
- Publication Type:Journal Article
- Keywords:
Hypertension/CO/ET;
Fatty liver/CO/ET;
Metabolic syndrome X
- From:
Journal of Chinese Physician
2009;11(3):329-331
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between metabolic syndrome(MS)and nonalcoholic fatty liver disease (NAFLD)in non-obese and non-diabetic hypertensive patients.Method 84 non-obese and non-diabetic hyperlensive patients were divided into 42 hypertensive patients with NAFLD and 42 hypertensive patients without NAFLD by abdominal ultrasonography examination.Body mass index(BMI),blood pressure,fast and OGGT 2 hour plasma glucose,fast and OGGT 2 hour plasma insulin,plasma lipids and aminotransferase were measured in the two groups.Multivariate logistic regression analysis was used to identify the variables independently associated with MS.Result BMI,triglycerides,fast insulin,2 hour insulin,aminotransferase,HOMA-IB and MS prevalence rate in the group with NAFLD were significantly higher than these in the group without NAFLD.Multivariate logistic regression analysis(forward LR)showed NAFLD:were independently associated with MS.Conclusion MS play a role not only in occurrence of NAFLD but also in liver injury.
