Changes of biochemical markers of bone turnover and bone mineral density in mid- and old-aged women

VernacularTitle:中老年妇女骨转换生化指标和骨密度的变化
Author: Hong LIU ; Eryuan LIAO ; Xianping WU ; Hong ZHANG ; Hui XIE ; Xingzhi CAO
Publication Type:Journal Article
Keywords: Biochemical markers of bone turnover; Bone mineral density; Menopause
From: Chinese Journal of Endocrinology and Metabolism 2009;25(2):164-167
CountryChina
Language:Chinese
Abstract: Objective To study the changes of biochemical markers of bone turnover and bone mineral density (BMD) in mid- and old-aged women.Methods A total of 408 female volunteers aged 40 to 86 years were enrolled.Serum bone alkaline phosphatase (BAP),osteoealtin and urine type I collagen N-telopeptide(uN'TX) were measured using ELISA,and BM D at anteroposterior lumbar spine 1-4(L1-4)and femoral neck (FN) was detected by dual energy X-ray absorptiometry (QDR4500A).Results (1) Serum BAP,osteocaltin and uNTX levels were positively correlated with age,parity,number of births and duration of menopause (all P