Neuroendocrine tumors of pancreas: treatment and survival analysis

VernacularTitle:胰腺神经内分泌肿瘤的治疗及生存分析
Author: Chonye SHI ; Dayong JIN ; Dansong WANG ; Xuefeng XU ; Tiantao KUANG ; Wenhui LOU
Publication Type:Journal Article
Keywords: Pancreas; Neureendocrine tumors; Surgical procedures,operative; Survival
From: Chinese Journal of Pancreatology 2009;9(1):18-20
CountryChina
Language:Chinese
Abstract: Objective To analyze the surgical treatment strategy and prognostic factors of pancreatic neuroendocrine tumor. Methods The clinical data of 30 patients who underwent pancreatic surgery in our department from April, 1999 to May, 2007 were retrospectively reviewed. According to the new WHO classification system, factors possibly influence the long term survival, such as tumor size, operation types, pathological types, were analyzed. Results There were 18 males and 12 females, with a mean age of 54 years old (28 ～ 78 years old). Five patients were lost in follow up. Among 25 patients who were completely followed, 20 cases were benign and other 5 were malignant, the median survival time of benign and malignant group was 74.8 months and 33.8 months, respectively (X2 = 8.90, P = 0.003). Overall 1, 2, 3, 4, 5-year survival rates were 100%, 100%, 82. 0%, 82. 0%, 65. 6%, respectively. Conclusions Pancreatic neuroendocrine tumor was a rare type of tumor of the pancreas with a good prognosis if surgically resected. The new classification method was effective in predicting the prognosis.