Analysis of factors affecting the prognosis of patients with Graves' disease treated with antithyroid drugs
10.3760/cma.j.issn.1000-6699.2009.02.019
- VernacularTitle:影响甲亢患者药物治疗预后的因素分析
- Author:
Yikai YU
;
Muzun ZHANG
;
Shuhong HU
;
Hongxia SHUAI
;
Aiping ZHANG
- Publication Type:Journal Article
- Keywords:
TSH receptor antibody;
Serum total iodine;
CD80;
Graves'disease;
Prognosis
- From:
Chinese Journal of Endocrinology and Metabolism
2009;25(2):184-185
- CountryChina
- Language:Chinese
-
Abstract:
A total of 96 patients with Graves'disease(GD)were followed for one and half years to observe the effect of antithyroid drugs(ATD)treatment.Serum TRAb,total iodine concentration and CD80 mRNA expression of peripheral blood monouclear ceils were measured.Logistics regression analysis was conducted with the combination of above parameters.Those GD patients with high level of TRAb,positive family history of GD, increased expression of CD80 and early age of onset were more inclined to relapse after ATD treatment.
