The transition of uropathogens and drug resistance in patients with type 2 diabetes in recent 10 years
10.3760/cma.j.issn.1674-2397.2009.02.005
- VernacularTitle:近10年2型糖尿病患者尿路感染致病菌及耐药性变迁
- Author:
Lizhen MA
;
Lingying YU
;
Chu ZHANG
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 2;
Urinary tract infection;
Pathogens;
Drug resistance
- From:
Chinese Journal of Clinical Infectious Diseases
2009;2(2):78-81
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the transition of uropathogens and drug resistance in patients with type 2 diabetes(T2DM)complicated with urinary tract infection(UTI)in recent 10 years.Methods A total of 392 cases of T2DM with UTI were included in the study.The patients were divided into 2 groups according to time of hospitalization:group A(January 1998 to December 2002)and group B(January 2003 to December 2007).Clinical information,distilbution of uropathogens and antibiotic resistance between the two groups were analyzed.Results The most common pathogens isolated were Escherichia coli(50/152,32.89%),followed by Candida albicans(21/152,13.82%)and Enterococcus faecium(15/152,9.87%).Of the various pathogenic organisms isolated in group B,there were 16 new species not seen in group A.Escherichia coli was found to have higher resistant rates to ciprofloxacin and ceftriaxone in group B than in group A(80.8%vs.42.8%,26.9%vs.0,respectively).Enterococcus faecium was found to be more susceptibility to tetracycline in group B than in group A(0 vs.100.O%).Conclusion Species of uropathogens in T2DM patients ale increased,and the isolates are of high drug resistance,which should be noted in clinic.
