Randomized controlled study on selective hepatic vascular versus complete clamping in hepatectomy
10.3760/cma.j.issn.1673-4203.2009.04.008
- VernacularTitle:选择性与全肝人肝血流阻断法在肝切除术应用的随机对照研究
- Author:
Guanggang LI
;
Qinghe TANG
;
Siyuan FU
;
Weiping ZHOU
- Publication Type:Journal Article
- Keywords:
hepatectomy;
selective liver inflow occlusion;
randomized controlled study
- From:
International Journal of Surgery
2009;36(4):235-238
- CountryChina
- Language:Chinese
-
Abstract:
Objective To valuate different effects in hepatectomy of three inflow occlusion methods including pringle maneuver, hemihepatic occlusion and portal venous occlusion. Methods 180 patients undergoing hepatectomy were randomly assigned to pringle group (group A), hemehepatic occlusion group (group B)or PV occlusion group (group C). The amount of blood lost, measurements of liver enzymes alanine aminotransferase (ALT), aspirate aminotransferase (AST), total bilirubin (TB), Serum albumin (ALB) and postoperative complication were also recorded. Results There was no operative mortality. One patient in group B changed into pringle maneuver due to the difficulties in dissecting the hemi-hepatic portal and was excluded. The amount of hemorrhage of three groups had no statistical difference. The ALT, AST, ALB and TB level of 1,3,7 days after operation had significant differences in three groups. The pringle group had a higher level ALT,AST,TB and lower ALB level than the other two groups. Conclusions All techniques of occlusion are effective and feasible for patients undergoing hepatectomies. However, compared with pringle maneuver, PV clamping and hemihepatic occlusion can relieve the liver function damage after hepatectomy.