The diagnosis and management and prevention of spontaneous renal allograft rupture
10.3760/cma.j.issn.1673-4904.2009.11.019
- VernacularTitle:移植肾自发性破裂的诊治和预防
- Author:
Jian GAO
;
Dongxi LUO
;
Jing GONG
;
Yong YANG
;
Lei CHEN
;
Bin ZENG
;
Aizhi LIU
- Publication Type:Journal Article
- Keywords:
Kidney transplantation;
Rupture,spontaneous;
Diagnosis;
Therapy
- From:
Chinese Journal of Postgraduates of Medicine
2009;32(11):47-49
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the diagnosis and management and prevention of spontaneous renal allograft rupture. Methods A retrospective analysis of 12 spontaneous renal allograft rupture was conducted. Clinical presentations were similar in all patients: sudden pain and swelling over the graft and declining blood pressure accompanied by anufia. Color-ultrasound combined with clinical manifestation had higher sensitive in detecting a case. Eleven cases were performed emergency operation, 3 of them lost their kidneys, 8 of them were performed transplant-preserving operation,2 cases lost their allograft because of rerupture of the kidney. Conservative therapy was carried on 1 case. Results Five cases of transplant nephrectomy were given hemodialysis to maintain, 6 eases who had accepted surgery to retain kidney transplantation and 1 case of using conservative treatment were cured and discharged. Conclusions Acute rejection and acute tubular necrosis are the main causes of spontaneous renal allograft rupture. Color-ultrasound combined with clinical manifestation have higher sensitive in detecting a case. As soon as possibly adopting internal medicine, surgery for a joint deal with the breakdown of renal aUograft rupture is important.Prevention should begin with the removal of the kidney, operation of the renal graft, rational use of immunodepressants, and early management of transplant rejection.