Efficiency and safety of large-dose alcohol sclerotherapy in treating hepatic cyst from the perspective of blood alcohol concentration
10.3760/cma.j.Issn.1004-4477.2009.04.021
- VernacularTitle:大剂量乙醇冲洗法治疗肝囊肿疗效及血乙醇浓度安全性的研究
- Author:
Yanhong FENG
;
Linxue QIAN
;
Yu GUI
;
Haima GONG
;
Qing ZHANG
- Publication Type:Journal Article
- Keywords:
Uhrasonography;
Liver diseases;
Cysts;
Ethanol/therapeutic use;
Sclerotherapy
- From:
Chinese Journal of Ultrasonography
2009;18(4):320-322
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the safety and efficiency of large-dose alcohol sclerotherapy in treating simple hepatic cyst. Methods Patients with hepatic cyst were divided into two groups. One group with 49 patients was treated with small-dose (<80 ml) absolute alcohol instillation. The other one with 32 patients was treated with large-dose (≥80 ml) absolute alcohol instillation. Blood alcohol concentration (BAC) was recorded right after and 30 rain, 1 h,2 h,3 h after the treatment. Diameter of cyst as a parameter of efficiency was recorded and compared between two groups during 1 year follow-up visit. Results Large-dose group was significantly more efficient in treating hepatic cyst than small-dose group. All BAC records were within the safe range and below the legal limit after drinking. BAC reached its peak 30 minutes after the treatment began and then decreased gradually. A significant correlation was found between BAC and the alcohol dosage. Conclusions Ultrasound-guided sclerotherapy with repeated large-dose absolute alcohol instillation is a safe and efficient treatment for simple hepatic cyst from the perspective of BAC.
