Clinical value of contrast-enhanced ultrasound in the interventional therapy response of hepatocellular carcinoma

VernacularTitle:超声造影对肝癌介入治疗局部疗效评估的临床价值
Author: Qin SI ; Wei TONG ; Xiaoli QIAN ; Shengxi HUANG ; Xiaoping LU
Publication Type:Journal Article
Keywords: Ultrasonography; Microbubbles; Liver neoplasms; Treatment outcome
From: Chinese Journal of Ultrasonography 2009;18(4):326-328
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical value of contrast-enhanced ultrasonography(CEUS) in evaluating treatment response of hepatocellular carcinoma after interventional therapy. Methods One hundred and three patients with 136 lesions of hepatocellular carcinoma confirmed by pathology were examined by common color ultrasound (US), contrast-enhanced CT, CEUS and DSA pre- and post-interventional treatment respectively. Results The sensitivity,specificity and accuracy of CEUS for focus judgment after interventional therapy were 95.8%, 95.6% and 98. 5% respectively. The sensitivity, specificity and accuracy of US in detecting tumor deactivation and residue were 92.3% ,77.4% and 83.1% respectively. CEUS were highly consistent with the results of enhanced CT/DSA (Kappa = 0.93) and significantly higher than those of US (Kappa = 0.66). Conclusions CEUS is useful to monitor the efficacy and guide treatment after interventional therapy.