Progress in the study on neuronal differentiation of bone marrow-derived mesenchymal stem cells in vitro
10.3760/cma.j.issn.1673-4181.2009.02.015
- VernacularTitle:骨髓间充质干细胞向神经细胞体外诱导分化的研究进展
- Author:
Haiyin ZHANG
;
Ji FENG
;
Yimin ZHOU
- Publication Type:Journal Article
- Keywords:
Bone marrow mesonchymal stem cells;
In vitro;
Induction;
Neural cells
- From:
International Journal of Biomedical Engineering
2009;32(2):121-124
- CountryChina
- Language:Chinese
-
Abstract:
Bone marrow-derived mesenchymal stem cells(BMSCs)exist in and can be isolated from the bone marrow of adult human being and animals and can be induced to differentiate into different cells.They are easy to be isolated,cultivated,and amplified.They are also less immunogenic in the body and can avoid ethical dispute when applied in transplantation.Studies have shown that BMSCs can be induced to differentiate into neural cells under certain conditions in vitro.This article reviewed the recent development in the research on the induction protocols for neural differentiation of BMSCs and the possible mechanisms.
