Relationships between calcium and the functions of immunocells and the immune deficiency disorders
10.3760/cma.j.issn.1674-635X.2009.01.018
- VernacularTitle:钙与免疫细胞功能及免疫缺陷疾病的关系
- Author:
Li WANG
;
Meiqin CAI
- Publication Type:Journal Article
- Keywords:
Calcium;
Immunocells;
Immune deficiency disorder
- From:
Chinese Journal of Clinical Nutrition
2009;17(1):60-63
- CountryChina
- Language:Chinese
-
Abstract:
Calcium, as a crucial signal molecule, plays an important role in the development process of immune cells and their functions. After T cell receptors or B cell receptors are stimulated or co-stimulated, the signaling pathways lead to Ca2+ influx and induce the increase of Ca2+ level in cells. Ca2+ signals have different short-time and long- term functions on T and B lymphocytes. Many immune deficiency disorders are resulted from the decrease of Ca2+ influx. This article reviewed the effects of calcium on the functions of T and B lymphocytes and its relationship with some immune deficiency disorders.
